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Simple Device Analyzes Cancer Tumor Cells in the Blood With the Potential of Measuring Treatment Response

Watch NBC News anchorman Brian Williams report on the CTC technology with interviews with Daniel A. Haber, MD, PhD


 

Massachusetts General Hospital (MGH) investigators have shown that a microchip-based device that detects and analyzes tumor cells in the bloodstream can be used to determine the genetic signature of lung tumors, allowing identification of those appropriate for targeted treatment. A pilot study of the device called the CTC-chip appears in the July 24 New England Journal of Medicine.
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Researchers Identify Cancer Outcome Predictor
A recent study by Rebecca Heist, MD, MPH, and colleagues, published in the Journal of Clinical Oncology, showed that two variations of the angiogenesis gene VEGF were associated with significant survival differences in early stage non-small cell lung cancer. Plans are underway to assess whether these genetic variations may help predict which treatments will be most beneficial.



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